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TC-S 7010 (Aurora A Inhibitor I)

TC-S 7010 (Aurora A Inhibitor I)

Name: TC-S 7010 (Aurora A Inhibitor I)
SKU: A10100

目录号: A10100

Aurora A 抑制剂

TC-S 7010 (Aurora A Inhibitor I) Chemical Structure

CAS NO. 1158838-45-9

TC-S 7010 (Aurora A Inhibitor I)是Aurora A激酶（AurA）的有效和选择性抑制剂，IC50值为3.4 nM（Aurora A），对Aurora B具有极高的选择性1000倍；用于研究Aurora A激酶的细胞作用的有用工具化合物。

库存：现货

规格	价格	数量
5 mg	￥ 600.00
10 mg	￥ 1,100.00
50 mg	￥ 3,800.00
100 mg	￥ 6,000.00
10mM * 1mL in DMSO	￥ 970.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

靶点信息

Aurora A (Cell-free assay)	Aurora C (Cell-free assay)	Aurora B (Cell-free assay)
3.4 nM	432 nM	3.4 μM

溶解度 *

In vitro (25°C)	DMSO	105 mg/mL (178.54 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	1.18 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17 mL	85.02 mL	170.04 mL
0.5 mM	3.4 mL	17 mL	34.01 mL
1 mM	1.7 mL	8.5 mL	17 mL
5 mM	0.34 mL	1.7 mL	3.4 mL

*The above data is based on the productmolecular weight 588.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10100
作用机制	Inhibitor (抑制剂)
M. Wt	588.1
Formula	C31H31ClFN7O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1158838-45-9
Synonyms	TC-S7010, TC-S-7010, TCS7010, TCS-7010
SMILES	CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F