TC-S 7010 (Aurora A Inhibitor I)

目录号: A10100

Aurora A Inhibitor

TC-S 7010 (Aurora A Inhibitor I) Chemical Structure

CAS NO. 1158838-45-9

Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.

库存: 缺货

规格 价格
5 mg
¥ 600.00
10 mg
¥ 1,100.00
50 mg
¥ 3,800.00
100 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 970.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.

Targets
Aurora A (Cell-free assay) Aurora C (Cell-free assay) Aurora B (Cell-free assay)
3.4 nM432 nM3.4 μM
In vitro DMSO 118 mg/mL (200.65 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17 mL 85.02 mL 170.04 mL
0.5 mM 3.4 mL 17 mL 34.01 mL
1 mM 1.7 mL 8.5 mL 17 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 588.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10100
MECHANISM OF ACTION Inhibitor
M. Wt 588.1
Formula C31H31ClFN7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1158838-45-9
Synonyms TC-S7010, TC-S-7010, TCS7010, TCS-7010
SMILES CCN1CCN(CC1)C(=O)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=C(C=C4)C(=O)NC5=CC=CC=C5Cl)F

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