AV412
目录号: A15460
EGFR 抑制剂
AV-412(MP412)是一种EGFR抑制剂,其IC50分别为0.75、0.5、0.79、2.3、19 nM,针对EGFR、EGFRL858R、EGFRT790M、EGFRL858R/T790M 和 ErbB2。
Discription | AV-412 (MP412) is an EGFR inhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19 nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively. | |||||
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Cell Research |
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目录号 | A15460 |
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分子式 | C27H28ClFN6O |
分子量 | 507.02 |
CAS号 | 451492-95-8 |
SMILES | CC(C)(C#CC1=CC2=C(C=C1NC(=O)C=C)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)N4CCN(CC4)C |
其他名称 | av 412, av-412, MP 412, MP-412 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2