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AVL-292 benzenesulfonate

BTK 抑制剂

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产品目录号: A15008


产品名 目录号 价格 数量
AVL-292 benzenesulfonate 10mg A15008-10
¥ 1,200.00
AVL-292 benzenesulfonate 50mg A15008-50
¥ 3,500.00
AVL-292 benzenesulfonate 100mg A15008-100
¥ 5,400.00



AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.

AVL-292 benzenesulfonate




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Chemical Information

目录号 A15008
Mechanism of action Inhibitor
分子量 581.62
化学分子式 C28H28FN5O6S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1360053-81-1
Synonyms AVL292 benzenesulfonate, AVL 292 benzenesulfonate
SMILES code COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O
化学名称 7-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)amino)heptanoic acid


AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.19 mL 85.97 mL 171.93mL
0.5 mM 3.44 mL 17.19 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.19 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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