AVL-292 benzenesulfonate

目录号: A15008

BTK inhibitor

AVL-292 benzenesulfonate Chemical Structure

CAS NO. 1360053-81-1

AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
50 mg
¥ 3,500.00
100 mg
¥ 5,400.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.19 mL 85.97 mL 171.93 mL
0.5 mM 3.44 mL 17.19 mL 34.39 mL
1 mM 1.72 mL 8.6 mL 17.19 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15008
MECHANISM OF ACTION Inhibitor
M. Wt 581.62
Formula C28H28FN5O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1360053-81-1
Synonyms AVL292 benzenesulfonate, AVL 292 benzenesulfonate
SMILES COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O

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