Spebrutinib besylate (AVL-292 benzenesulfonate)
目录号: A15008
BTK 抑制剂
AVL-292苯磺酸盐是一种共价的、高度选择性的、口服活性的小分子抑制剂,专门针对Btk,其IC50值为0.5 nM,对其他检测的激酶具有超过1400倍的选择性。
Discription | AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed. |
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目录号 | A15008 |
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分子式 | C28H28FN5O6S |
分子量 | 581.62 |
CAS号 | 1360053-81-1 |
SMILES | COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O |
其他名称 | AVL292 benzenesulfonate, AVL 292 benzenesulfonate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2