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Spebrutinib besylate (AVL-292 benzenesulfonate)

目录号: A15008
BTK 抑制剂
AVL-292苯磺酸盐是一种共价的、高度选择性的、口服活性的小分子抑制剂,专门针对Btk,其IC50值为0.5 nM,对其他检测的激酶具有超过1400倍的选择性。
Grouped product items
规格 价格 库存 数量
10mg
¥5,600.00
现货
25mg
¥10,500.00
现货
50mg
¥13,300.00
现货
100mg
¥16,940.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription AVL-292 benzenesulfonate is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM, >1400-fold selectivity over the other kinases assayed.
产品信息
目录号 A15008
分子式 C28H28FN5O6S
分子量 581.62
CAS号 1360053-81-1
SMILES COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F.C1=CC=C(C=C1)S(=O)(=O)O
其他名称 AVL292 benzenesulfonate, AVL 292 benzenesulfonate
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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