Trusted by 10,000+ Scientists since 2006
微信关注
申请试用装

AVL-292

促销

Btk 抑制剂

0 Customer Reviews
产品目录号: A13202

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AVL-292 5mg A13202-5
¥ 600.00
AVL-292 10mg A13202-10
¥ 900.00
AVL-292 25mg A13202-25
¥ 1,700.00
AVL-292 50mg A13202-50
¥ 2,600.00
AVL-292 10mM * 1mL in DMSO A13202-10mM-D
¥ 650.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AVL-292 is a highly selective, covalent Btk inhibitor.

AVL-292

双击上述图片即可查看完整大小

缩小
放大

更多视图

顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A13202
Mechanism of action Inhibitor
分子量 423.44
化学分子式 C22H22FN5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1202757-89-8
Synonyms AVL292, AVL 292, CC292, CC-292, CC 292
SMILES code COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
化学名称 N-(3-((5-fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide

生物活性

Description
AVL-292 is a highly selective, covalent Btk inhibitor.
Targets
Target Value
BTKIC50: <0.5nM
YESIC50: 723nM
c-SrcIC50: 1.729μM
BRKIC50: 2.43μM
LynIC50: 4.401μM
FynIC50: 7.146μM
LCKIC50: 9.079μM
CSKIC50: >10μM
HckIC50: 14.46μM

溶解性

Solubility (25°C)* In vitro DMSO 85 mg/mL (200.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.62 mL 118.08 mL 236.16mL
0.5 mM 4.72 mL 23.62 mL 47.23 mL
1 mM 2.36 mL 11.81 mL 23.62 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

产品标签

使用空格分隔标签。使用单引号(')标注词组。


Keywords:购买 AVL-292 | AVL-292 供应商 | 订购 AVL-292 | AVL-292 价格 | AVL-292 生产商 | 订单 AVL-292 | AVL-292 代理商 | 购买 1202757-89-8| 1202757-89-8 供应商 | 订购 1202757-89-8 | 1202757-89-8 价格 | 1202757-89-8 生产商 | 订单 1202757-89-8 | 1202757-89-8 代理商|buy AVL-292 | AVL-292 Supplier | purchase AVL-292 | AVL-292 cost | AVL-292 manufacturer | order AVL-292 | AVL-292 distributor | buy 1202757-89-8| 1202757-89-8 Supplier | purchase 1202757-89-8 | 1202757-89-8 cost | 1202757-89-8 manufacturer | order 1202757-89-8 | 1202757-89-8 distributor