AY77

Name: AY77
SKU: A23887
Price: 2835 CNY
Rating: 5 (288 reviews)

目录号: A23887

PAR2 激动剂

AY77 是一种偏向钙的 PAR2 激动剂。AY77 在 PAR2 介导的 Gq 通路激活和 β-arrestin-2 的招募方面，分别显示出 0.17 和 2 nM 的 EC50。AY77 强效地诱导细胞内 Ca2+ 释放。

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规格	价格	库存
1mg	¥2,835.00	现货
5mg	¥6,160.00	现货
10mg	¥8,295.00	现货
25mg	¥12,355.00	现货
50mg	¥16,695.00	现货
100mg	¥22,575.00	现货
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Data Sheet

SDS

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生物活性

Discription

AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A23887
分子式	C21H32N4O4
分子量	404.5
CAS号	1835734-92-3
Sequence	{5-Isoxazolylcarbonyl-Cha}-{Chg}-NH2
Sequence shortening	{5-Isoxazolylcarbonyl-Cha}-{Chg}-NH2

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