AZ191
目录号: A14314
DYRK 抑制剂
AZ191 是一种强效且选择性的 DYRK1B 抑制剂,其 IC50 为 17 nM,相较于 DYRK1A 和 DYRK2 分别具有约 5 倍和 110 倍的选择性。
Discription | AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2. | |||||
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Targets |
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Cell Research |
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目录号 | A14314 |
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分子式 | C24H27N7O |
分子量 | 429.52 |
CAS号 | 1594092-37-1 |
SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC |
其他名称 | AZ 191, AZ-191 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 81 mg/mL (188.58 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (2.32 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.28 mL | 116.41 mL | 232.82 mL |
0.5 mM | 4.66 mL | 23.28 mL | 46.56 mL |
1 mM | 2.33 mL | 11.64 mL | 23.28 mL |
5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2