AZ31

Name: AZ31
SKU: A16813
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A16813

ATM 抑制剂

AZ31 是一种选择性和新颖的 ATM 抑制剂，其 IC50 值小于 0.0012 μM。它对于相关酶具有极好的选择性（对 DNA-PK 和 PI3Kα 选择性超过 500 倍，对 mTOR、PI3Kβ 和 PI3Kγ 选择性超过 1000 倍）。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥665.00	现货
25mg	¥1,155.00	现货
50mg	¥1,750.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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Data Sheet

SDS

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生物活性

Discription

AZ31 is a selective and novel ATM inhibitor with an IC50 of <0.0012 μM. It shows excellent selectivity over closely related enzymes (>500 fold selective over DNA-PK and PI3Kα and >1000 fold selective over mTOR, PI3Kβ and PI3Kγ).

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16813
分子式	C24H28N4O3
分子量	420.5
CAS号	2088113-98-6
SMILES	NC(C1=C(N[C@H](C2CCOCC2)C)C3=CC(C4=CN=C(COC)C=C4)=CC=C3N=C1)=O
其他名称	AZ 31, AZ-31
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	46 mg/mL (109.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.78 mL	118.91 mL	237.81 mL
0.5 mM	4.76 mL	23.78 mL	47.56 mL
1 mM	2.38 mL	11.89 mL	23.78 mL
5 mM	0.48 mL	2.38 mL	4.76 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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