AZ3451
目录号: A20204
PAR2 拮抗剂
AZ3451 是一种强效的蛋白酶激活受体-2（PAR2）拮抗剂，其半抑制浓度（IC50）为23纳摩尔。
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生物活性
| Discription | AZ3451 is a potent protease-activated receptor-2 (PAR2) antagonist with IC50 of 23 nM. |
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产品信息
| 目录号 | A20204 |
|---|---|
| 分子式 | C30H27BrN4O3 |
| 分子量 | 571.46 |
| CAS号 | 2100284-59-9 |
| SMILES | O=C(C1=CC=C2C(N=C(C3=C(Br)C=C(OCO4)C4=C3)N2[C@H](C5CCCCC5)C)=C1)NC6=CC=C(C#N)C=C6 |
| 其他名称 | AZ 3451, AZ-3451 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 97 mg/mL (169.74 mM) | |
| Water | Insoluble | ||
| Ethanol | 97 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.5 mL | 87.5 mL | 174.99 mL |
| 0.5 mM | 3.5 mL | 17.5 mL | 35 mL |
| 1 mM | 1.75 mL | 8.75 mL | 17.5 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.5 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2100284-59-9 | 2100284-59-9 供应商 | 2100284-59-9 花费 | 2100284-59-9 生产商 | 订购 2100284-59-9 | 2100284-59-9 代理商