|Mechanism of action||Inhibitor|
|储存方式||at -20°C 2 years|
|Synonyms||AZ-6102, AZ 6102|
|化学名称||4H-?Pyrrolo[2,?3-?d]?pyrimidin-?4-?one, 2-?[4-?[6-?[(3R,?5S)?-?3,?5-?dimethyl-?1-?piperazinyl]?-?4-?methyl-?3-?pyridinyl]?phenyl]?-?3,?7-?dihydro-?7-?methyl-?, rel-|
|AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.|
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||23.34 mL||116.68 mL||233.36mL|
|0.5 mM||4.67 mL||23.34 mL||46.67 mL|
|1 mM||2.33 mL||11.67 mL||23.34 mL|
|5 mM||0.47 mL||2.33 mL||4.67 mL|
*The above data is based on the productmolecular weight 428.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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