AZ6102
目录号: A15873
TNKS1/2 抑制剂
AZ6102 是一种强效的 TNKS1/2 抑制剂，相对于其他 PARP 家族酶 具有 100 倍的选择性，并在 DLD-1 细胞中显示出对 Wnt 通路 抑制的 IC50 为 5 nM。
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生物活性
| Discription | AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells. | ||
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产品信息
| 目录号 | A15873 |
|---|---|
| 分子式 | C25H28N6O |
| 分子量 | 428.53 |
| CAS号 | 1645286-75-4 |
| SMILES | C[C@H]1CN(C2=NC=C(C3=CC=C(C4=NC(C(C=CN5C)=C5N4)=O)C=C3)C(C)=C2)C[C@@H](C)N1 |
| 其他名称 | AZ-6102, AZ 6102 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 83 mg/mL (193.68 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.34 mL | 116.68 mL | 233.36 mL |
| 0.5 mM | 4.67 mL | 23.34 mL | 46.67 mL |
| 1 mM | 2.33 mL | 11.67 mL | 23.34 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.67 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1645286-75-4 | 1645286-75-4 供应商 | 1645286-75-4 花费 | 1645286-75-4 生产商 | 订购 1645286-75-4 | 1645286-75-4 代理商