Trusted by 10,000+ Scientists since 2006


Raf 抑制剂

0 Customer Reviews
产品目录号: A11063


产品名 目录号 价格 数量
AZ628 5mg A11063-5
¥ 700.00
AZ628 10mg A11063-10
¥ 1,100.00
AZ628 25mg A11063-25
¥ 2,200.00
AZ628 50mg A11063-50
¥ 3,600.00
AZ628 10mM * 1mL in DMSO A11063-10mM-D
¥ 750.00



AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11063
Mechanism of action Inhibitor
分子量 451.5
化学分子式 C27H25N5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 878739-06-1
Synonyms AZ-628
SMILES code CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
化学名称 3-(1-Cyano-1-methylethyl)-N-[3-[(3,4-dihydro-3-methyl-4-oxo-6-quinazolinyl)amino]-4-methylphenyl]benzamide


AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
C-Raf-1 (Cell-free assay) B-Raf (V600E) (Cell-free assay) B-Raf (Cell-free assay)
29 nM34 nM105 nM


Solubility (25°C) * In vitro DMSO 90 mg/mL (199.32 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.15 mL 110.74 mL 221.48mL
0.5 mM 4.43 mL 22.15 mL 44.3 mL
1 mM 2.21 mL 11.07 mL 22.15 mL
5 mM 0.44 mL 2.21 mL 4.43 mL

*The above data is based on the productmolecular weight 451.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.




Similar product(s)

Keywords:购买 AZ628 | AZ628 供应商 | 订购 AZ628 | AZ628 价格 | AZ628 生产商 | 订单 AZ628 | AZ628 代理商 | 购买 878739-06-1| 878739-06-1 供应商 | 订购 878739-06-1 | 878739-06-1 价格 | 878739-06-1 生产商 | 订单 878739-06-1 | 878739-06-1 代理商|buy AZ628 | AZ628 Supplier | purchase AZ628 | AZ628 cost | AZ628 manufacturer | order AZ628 | AZ628 distributor | buy 878739-06-1| 878739-06-1 Supplier | purchase 878739-06-1 | 878739-06-1 cost | 878739-06-1 manufacturer | order 878739-06-1 | 878739-06-1 distributor