|C-Raf-1 (Cell-free assay)||B-Raf (V600E) (Cell-free assay)||B-Raf (Cell-free assay)|
|29 nM||34 nM||105 nM|
|In vitro (25°C)||DMSO||90 mg/mL (199.32 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.15 mL||110.74 mL||221.48 mL|
|0.5 mM||4.43 mL||22.15 mL||44.3 mL|
|1 mM||2.21 mL||11.07 mL||22.15 mL|
|5 mM||0.44 mL||2.21 mL||4.43 mL|
*The above data is based on the productmolecular weight 451.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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