Azaindole 1 (BAY-549)

Name: Azaindole 1 (BAY-549)
SKU: A15225
Price: 770 CNY
Rating: 5 (2 reviews)

目录号: A15225

ROCK 抑制剂

2 篇发表文献

Azaindole 1 (BAY-549) 是一种高效的抑制剂，能够抑制人类的 ROCK-1 和 ROCK-2 异构酶，其 IC50 值分别为 0.6 nM 和 1.1 nM。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
5mg	¥1,960.00	现货
10mg	¥3,115.00	现货
25mg	¥5,320.00	现货
50mg	¥7,455.00	现货
100mg	¥10,115.00	现货
*10mM 1mL in DMSO**	¥2,695.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Azaindole 1 (BAY-549)发表的2篇文献

Delia Talpan, .et al. , Int J Mol Sci, 2023, Jan 11;24(2):1461 PMID: 36674976

Nina Seidelmann, .et al. , J Cell Mol Med, 2021, Oct;25(20):9647-9659 PMID: 34486211

生物活性

Discription

Azaindole 1 (BAY-549) is a highly potent inhibitor of human ROCK-1 and ROCK-2 isoenzymes with IC50 values of 0.6 and 1.1 nM, respectively.

Targets

Target	Value

产品信息

目录号	A15225
分子式	C18H13ClF2N6O
分子量	402.79
CAS号	867017-68-3
SMILES	CC1=CNC2=NC=CC(=C12)OC3=C(C=C(C=C3F)NC4=CC(=NC(=N4)N)Cl)F
其他名称	ROCK-IN-2; TC-S 7001
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (191.16 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.96 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.83 mL	124.13 mL	248.27 mL
0.5 mM	4.97 mL	24.83 mL	49.65 mL
1 mM	2.48 mL	12.41 mL	24.83 mL
5 mM	0.5 mL	2.48 mL	4.97 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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