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Azasetron HCl是一种选择性的5-HT3受体拮抗剂，IC50为0.33 nM，用于治疗癌症化学疗法引起的恶心和呕吐。
| In vitro | DMSO | Insoluble | |
| Water | 3 mg/mL (7.76 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.89 mL | 129.44 mL | 258.89 mL |
| 0.5 mM | 5.18 mL | 25.89 mL | 51.78 mL |
| 1 mM | 2.59 mL | 12.94 mL | 25.89 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.18 mL |
*The above data is based on the productmolecular weight 386.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16417 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 386.27 |
| Formula | C17H20ClN3O3.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 123040-16-4 |
| Synonyms | Y-25130 hydrochloride, Y25130 hydrochloride, Y 25130 hydrochloride |
| SMILES | CN1C(=O)COC2=C1C=C(C=C2C(=O)NC3CN4CCC3CC4)Cl.Cl |
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