AZD 2932
目录号: A14156
mutil-targeted protein tyrosine kinase 抑制剂
AZD2932 是一种强效的多靶点蛋白酪氨酸激酶抑制剂，其半抑制浓度（IC50）分别为 VEGFR-2 8 nM、PDGFRβ 4 nM、Flt-3 7 nM 和 c-Kit 9 nM。
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生物活性
| Discription | AZD2932 is a potent and mutil-targeted protein tyrosine kinase inhibitor with IC50 of 8 nM, 4 nM, 7 nM, and 9 nM for VEGFR-2, PDGFRβ, Flt-3, and c-Kit, respectively. | |||||
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产品信息
| 目录号 | A14156 |
|---|---|
| 分子式 | C24H25N5O4 |
| 分子量 | 447.49 |
| CAS号 | 883986-34-3 |
| SMILES | CC(C)N1C=C(C=N1)NC(=O)CC2=CC=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC |
| 其他名称 | AZD-2932,AZD2932 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 78 mg/mL (174.3 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 4 mg/mL (8.94 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.35 mL | 111.73 mL | 223.47 mL |
| 0.5 mM | 4.47 mL | 22.35 mL | 44.69 mL |
| 1 mM | 2.23 mL | 11.17 mL | 22.35 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.47 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 883986-34-3 | 883986-34-3 供应商 | 883986-34-3 花费 | 883986-34-3 生产商 | 订购 883986-34-3 | 883986-34-3 代理商