AZD-3965

目录号: A14186

MCT1 抑制剂

AZD-3965

AZD-3965 Chemical Structure

CAS NO. 1448671-31-5

AZD-3965(AZD3965)是具有1.6 nM结合亲和力的单羧酸盐转运蛋白1(MCT1)的选择性抑制剂,是MCT2的6倍选择性,在10μM时不抑制MCT4。

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 1,500.00
25 mg
¥ 2,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AZD-3965(AZD3965)是具有1.6 nM结合亲和力的单羧酸盐转运蛋白1(MCT1)的选择性抑制剂,是MCT2的6倍选择性,在10μM时不抑制MCT4。
靶点信息
MCT1
In vitro DMSO 96 mg/mL (186.22 mM)
Water Insoluble
Ethanol 96 mg/mL (186.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.4 mL 96.99 mL 193.99 mL
0.5 mM 3.88 mL 19.4 mL 38.8 mL
1 mM 1.94 mL 9.7 mL 19.4 mL
5 mM 0.39 mL 1.94 mL 3.88 mL

*The above data is based on the productmolecular weight 515.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14186
作用机制 Inhibitor (抑制剂)
M. Wt 515.5
Formula C21H24F3N5O5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1448671-31-5
Synonyms AZD3965,AZD 3965
SMILES O=C1N(C(C)C)C2=C(C(C(N3OC[C@@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O

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