AZD-3965

Name: AZD-3965
SKU: A14186
Price: 315 CNY
Rating: 5 (1 reviews)

目录号: A14186

MCT1 抑制剂

1 篇发表文献

AZD3965 是一种选择性的 单羧酸转运蛋白1（MCT1）抑制剂，其结合亲和力为1.6 nM，对MCT2的选择性是6倍，且在10 μM浓度下不抑制MCT4。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
2mg	¥455.00	现货
5mg	¥770.00	现货
10mg	¥980.00	现货
25mg	¥1,785.00	现货
50mg	¥3,080.00	现货
100mg	¥5,740.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD-3965 发表的1篇文献

Lu Gao, .et al. , Int J Biol Sci, 2022, Jan 1;18(2):599-616 PMID: 35002512

生物活性

Discription

AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM.

Targets

Target	Value

产品信息

目录号	A14186
分子式	C21H24F3N5O5S
分子量	515.5
CAS号	1448671-31-5
SMILES	O=C1N(C(C)C)C2=C(C(C(N3OC[C@@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O
其他名称	AZD3965,AZD 3965
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	96 mg/mL (186.22 mM)
	Water	Insoluble
	Ethanol	96 mg/mL (186.22 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.4 mL	96.99 mL	193.99 mL
0.5 mM	3.88 mL	19.4 mL	38.8 mL
1 mM	1.94 mL	9.7 mL	19.4 mL
5 mM	0.39 mL	1.94 mL	3.88 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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