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AZD-4635 (HTL1071)是一种口服A2AR拮抗剂，可与人A2AR结合，Ki为1.7 nM，选择性比其他腺苷受体高30倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.67 mL | 158.36 mL | 316.73 mL |
| 0.5 mM | 6.33 mL | 31.67 mL | 63.35 mL |
| 1 mM | 3.17 mL | 15.84 mL | 31.67 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.33 mL |
*The above data is based on the productmolecular weight 315.73. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16820 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 315.73 |
| Formula | C15H11ClFN5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1321514-06-0 |
| Synonyms | AZD4635, AZD 4635, HTL-1071, HTL 1071 |
| SMILES | NC1=NC(C2=CC=C(F)C=C2)=C(C3=CC(C)=NC(Cl)=C3)N=N1 |
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