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CXCR2 拮抗剂

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产品目录号: A15941


产品名 目录号 价格 数量
AZD-5069 5mg A15941-5
¥ 1,500.00
AZD-5069 10mg A15941-10
¥ 2,500.00
AZD-5069 25mg A15941-25
¥ 5,000.00



AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD.





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Chemical Information

目录号 A15941
Mechanism of action Antagonist
分子量 476.51
化学分子式 C18H22F2N4O5S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 878385-84-3
Synonyms AZD 5069, AZD5069
SMILES code O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[C@H](C)[C@@H](O)CO)=C2)=O
化学名称 N-(2-((2,3-difluorobenzyl)thio)-6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide


AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.99 mL 104.93 mL 209.86mL
0.5 mM 4.2 mL 20.99 mL 41.97 mL
1 mM 2.1 mL 10.49 mL 20.99 mL
5 mM 0.42 mL 2.1 mL 4.2 mL

*The above data is based on the productmolecular weight 476.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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