产品详情
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is a Mcl-1 inhibitor with an IC50 of 6.3 μM in FRET assay and a Kd of 0.98 μM in surface plasmon resonance (SPR) assay.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.88 mL | 74.38 mL | 148.75 mL |
0.5 mM | 2.98 mL | 14.88 mL | 29.75 mL |
1 mM | 1.49 mL | 7.44 mL | 14.88 mL |
5 mM | 0.3 mL | 1.49 mL | 2.98 mL |
*The above data is based on the productmolecular weight 672.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21361 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 672.26 |
Formula | C35H34ClN5O3S2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 2143061-82-7 |
Synonyms | AZD5991, AZD 5991 |
SMILES | O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5 |
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