AZD-9291 (Osimertinib)

Name: AZD-9291 (Osimertinib)
SKU: A13681
Price: 175 CNY
Rating: 5 (4 reviews)

目录号: A13681

EGFR 抑制剂

4 篇发表文献

AZD-9291 是一种第三代 EGFR 抑制剂，在临床前研究中显示出潜力，并为那些对现有 EGFR 抑制剂 产生耐药性的晚期肺癌患者提供了希望。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥280.00	现货
10mg	¥350.00	现货
25mg	¥420.00	现货
50mg	¥525.00	现货
100mg	¥700.00	现货
200mg	¥770.00	现货
500mg	¥840.00	现货
1g	¥1,050.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of AZD-9291 (Osimertinib)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD-9291 (Osimertinib)发表的4篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Sang-Hyun Lee, .et al. , NPJ Precis Oncol, 2024, May 21;8(1):111 PMID: 38773241

Liyanage Manosika Buddhini Perera, .et al. , Biol Pharm Bull, 2024, 47(4):750-757 PMID: 38556260

Liu YN, .et al. , Int J Cancer, 2019, Jun 4 PMID: 31162839

生物活性

Discription

AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13681
分子式	C28H33N7O2
分子量	499.61
CAS号	1421373-65-0
SMILES	CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
其他名称	AZD 9291, AZD9291
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 90 mg/mL (180.14 mM)
	Water	Insoluble
	Ethanol	Warmed: 39 mg/mL (78.05 mM)
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	7.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.02 mL	100.08 mL	200.16 mL
0.5 mM	4 mL	20.02 mL	40.03 mL
1 mM	2 mL	10.01 mL	20.02 mL
5 mM	0.4 mL	2 mL	4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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