AZD-9291 (Osimertinib)

目录号: A13681

EGFR inhibitor

AZD-9291 (Osimertinib)

AZD-9291 (Osimertinib) Chemical Structure

CAS NO. 1421373-65-0

AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 700.00
25 mg
¥ 1,000.00
50 mg
¥ 1,200.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors.
Targets
L858R/T790M EGFR (LoVo cells) Exon 19 deletion EGFR (LoVo cells) WT EGFR (LoVo cells)
11.44 nM12.92 nM493.8 nM
In vitro DMSO 99 mg/mL heating (198.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol 43 mg/mL heating (86.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.02 mL 100.08 mL 200.16 mL
0.5 mM 4 mL 20.02 mL 40.03 mL
1 mM 2 mL 10.01 mL 20.02 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 499.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A13681
MECHANISM OF ACTION Inhibitor
M. Wt 499.61
Formula C28H33N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1421373-65-0
Synonyms AZD 9291, AZD9291
SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) 供应商 | 订购 AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) 价格 | AZD-9291 (Osimertinib) 生产商 | 订单 AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) 代理商 | 购买 1421373-65-0| 1421373-65-0 供应商 | 订购 1421373-65-0 | 1421373-65-0 价格 | 1421373-65-0 生产商 | 订单 1421373-65-0 | 1421373-65-0 代理商|buy AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) Supplier | purchase AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) cost | AZD-9291 (Osimertinib) manufacturer | order AZD-9291 (Osimertinib) | AZD-9291 (Osimertinib) distributor | buy 1421373-65-0| 1421373-65-0 Supplier | purchase 1421373-65-0 | 1421373-65-0 cost | 1421373-65-0 manufacturer | order 1421373-65-0 | 1421373-65-0 distributor
Rewards