AZD1080

目录号: A12819

GSK3 inhibitor

AZD1080 Chemical Structure

CAS NO. 612487-72-6

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

库存: 现货

规格 价格 数量
5 mg
¥ 1,600.00
10 mg
¥ 2,900.00
25 mg
¥ 5,200.00
50 mg
¥ 7,800.00
10mM * 1mL in DMSO
¥ 2,060.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Targets
GSK-3α GSK-3β
6.9 nM31 nM
In vitro (25°C) DMSO 52 mg/mL (155.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
目录号 A12819
MECHANISM OF ACTION Inhibitor
M. Wt N/A
Formula N/A
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 612487-72-6
Synonyms AZD 1080, AZD-1080
SMILES C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2

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