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AZD1080

促销

GSK3 抑制剂

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产品目录号: A12819

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AZD1080 5mg A12819-5
¥ 1,600.00
AZD1080 10mg A12819-10
¥ 2,900.00
AZD1080 25mg A12819-25
¥ 5,200.00
AZD1080 50mg A12819-50
¥ 7,800.00
AZD1080 10mM * 1mL in DMSO A12819-10mM-D
¥ 2,060.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.

AZD1080

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 AZD1080 发表的文献 (1)
  • Shengzhong Liu, .et al. STAT1 avtiviated LINC00961 regulates myocardial infarction by the PI3K/AKT/GSK3汕 signaling pathway, J Cell Biochem, 2019, 2019

Chemical Information

目录号 A12819
Mechanism of action Inhibitor
分子量 N/A
化学分子式 N/A
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 612487-72-6
Synonyms AZD 1080, AZD-1080
SMILES code C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2
化学名称 N/A

生物活性

Description
AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
Targets
GSK-3α GSK-3β
6.9 nM31 nM

溶解性

Solubility (25°C) * In vitro DMSO 52 mg/mL (155.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 0 mL 0 mL 0mL
0.5 mM 0 mL 0 mL 0 mL
1 mM 0 mL 0 mL 0 mL
5 mM 0 mL 0 mL 0 mL

*The above data is based on the productmolecular weight N/A. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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