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AZD1080

目录号: A12819
GSK3 抑制剂
AZD1080 是一种新型的 GSK3 抑制剂,能够挽救啮齿动物大脑中的突触可塑性缺陷,并在人体中展示外周靶点参与。
Grouped product items
规格 价格 库存 数量
1mg
¥210.00
现货
2mg
¥315.00
现货
5mg
¥490.00
现货
10mg
¥840.00
现货
25mg
¥1,575.00
现货
50mg
¥2,520.00
现货
100mg
¥3,115.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用AZD1080发表的1篇文献
  • Shengzhong Liu, .et al. , J Cell Biochem, 2019, 2019 PMID: 30887575
  • 生物活性
    Discription AZD1080 is a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans.
    Targets
    Target Value
    产品信息
    目录号 A12819
    分子式 C19H18N4O2
    分子量 334.4
    CAS号 612487-72-6
    SMILES C1COCCN1CC2=CN/C(=C\3/C4=C(C=CC(=C4)C#N)NC3=O)/C=C2
    其他名称 AZD 1080, AZD-1080
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 49 mg/mL (146.54 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 19 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 29.9 mL 149.52 mL 299.04 mL
    0.5 mM 5.98 mL 29.9 mL 59.81 mL
    1 mM 2.99 mL 14.95 mL 29.9 mL
    5 mM 0.6 mL 2.99 mL 5.98 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
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