AZD1981

Name: AZD1981
SKU: A13186

目录号: A13186

CRTH2 receptor 拮抗剂

AZD1981 Chemical Structure

CAS NO. 802904-66-1

AZD1981作为疾病相关细胞系统的有效拮抗剂，可抑制DK-PGD2诱导的人嗜酸性粒细胞CD11b表达，IC50为10 nM。

库存：现货

规格	价格	数量
5 mg	￥ 600.00
10 mg	￥ 1,000.00
25 mg	￥ 2,000.00
10mM * 1mL in DMSO	￥ 1,060.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

AZD1981作为疾病相关细胞系统的有效拮抗剂，可抑制DK-PGD2诱导的人嗜酸性粒细胞CD11b表达，IC50为10 nM。

靶点信息

CRTh2 (DP2) receptor
4 nM

溶解度 *

In vitro	DMSO	9 mg/mL (23.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.72 mL	128.58 mL	257.16 mL
0.5 mM	5.14 mL	25.72 mL	51.43 mL
1 mM	2.57 mL	12.86 mL	25.72 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 388.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13186
作用机制	Antagonist (拮抗剂)
M. Wt	388.87
Formula	C19H17ClN2O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	802904-66-1
Synonyms	AZD-1981, AZD 1981
SMILES	CC1=C(C2=C(N1CC(=O)O)C=CC=C2NC(=O)C)SC3=CC=C(C=C3)Cl