AZD1981
目录号: A13186
CRTH2 receptor 拮抗剂
AZD1981 是一种在疾病相关细胞系统中的强效拮抗剂，能够抑制 DK-PGD2 在人类嗜酸性粒细胞中诱导的 CD11b 表达，其 IC50 为 10 nM。
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生物活性
| Discription | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A13186 |
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| 分子式 | C19H17ClN2O3S |
| 分子量 | 388.87 |
| CAS号 | 802904-66-1 |
| SMILES | CC1=C(C2=C(N1CC(=O)O)C=CC=C2NC(=O)C)SC3=CC=C(C=C3)Cl |
| 其他名称 | AZD-1981, AZD 1981 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 9 mg/mL (23.14 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.72 mL | 128.58 mL | 257.16 mL |
| 0.5 mM | 5.14 mL | 25.72 mL | 51.43 mL |
| 1 mM | 2.57 mL | 12.86 mL | 25.72 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 802904-66-1 | 802904-66-1 供应商 | 802904-66-1 花费 | 802904-66-1 生产商 | 订购 802904-66-1 | 802904-66-1 代理商