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GSK-3?? 抑制剂

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产品目录号: A13060


产品名 目录号 价格 数量
AZD2858 10mg A13060-10
¥ 800.00
AZD2858 25mg A13060-25
¥ 1,600.00
AZD2858 50mg A13060-50
¥ 2,800.00
AZD2858 100mg A13060-100
¥ 5,000.00



AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A13060
Mechanism of action Inhibitor
分子量 453.52
化学分子式 C21H23N7O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 486424-20-8
Synonyms AZD-2858, AZD 2858
SMILES code CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
化学名称 Pyrazinecarboxamide,3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-


AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, activating Wnt signaling, increases bone mass in rats.
68 nM


Solubility (25°C) * In vitro DMSO 7 mg/mL (15.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.25 mL 220.5mL
0.5 mM 4.41 mL 22.05 mL 44.1 mL
1 mM 2.2 mL 11.02 mL 22.05 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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