AZD3759

目录号: A15551

EGFR inhibitor

AZD3759

AZD3759 Chemical Structure

CAS NO. 1626387-80-1

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR). It binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR.

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
25 mg
¥ 1,200.00
50 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR). It binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR.
Targets
EGFR (L858R) EGFR (exon 19Del) EGFR (WT)
0.2 nM0.2 nM0.3 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.74 mL 108.72 mL 217.44 mL
0.5 mM 4.35 mL 21.74 mL 43.49 mL
1 mM 2.17 mL 10.87 mL 21.74 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 459.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15551
MECHANISM OF ACTION Inhibitor
M. Wt 459.9
Formula C22H23ClFN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1626387-80-1
Synonyms AZD 3759
SMILES CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C

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