Zorifertinib (AZD3759)
目录号: A15551
EGFR 抑制剂
AZD3759 是一种可口服的表皮生长因子受体(EGFR)抑制剂。它能结合并抑制 EGFR 及其某些突变形式的活性。
| Discription | AZD3759 is an orally available inhibitor of the epidermal growth factor receptor (EGFR). It binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. | |||||
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| 目录号 | A15551 |
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| 分子式 | C22H23ClFN5O3 |
| 分子量 | 459.9 |
| CAS号 | 1626387-80-1 |
| SMILES | CC1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C |
| 其他名称 | AZD 3759 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 80 mg/mL (173.94 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 18 mg/mL (39.13 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.74 mL | 108.72 mL | 217.44 mL |
| 0.5 mM | 4.35 mL | 21.74 mL | 43.49 mL |
| 1 mM | 2.17 mL | 10.87 mL | 21.74 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.35 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2