AZD3839 free base

Name: AZD3839 free base
SKU: A21606
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A21606

BACE1 抑制剂

AZD3839 (free base) 是一种强效且选择性的 BACE1 抑制剂，IC50 为 23.6 uM，对 BACE2 的选择性约为 14 倍，同时也是一种 β-分泌酶抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥700.00	现货
10mg	¥1,190.00	现货
25mg	¥2,485.00	现货
50mg	¥4,620.00	现货
100mg	¥7,560.00	现货
*10mM 1mL in DMSO**	¥805.00	现货
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Data Sheet

SDS

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生物活性

Discription

AZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21606
分子式	C24H16F3N5
分子量	431.41
CAS号	1227163-84-9
SMILES	FC1=C2C([C@](C3=CC=CC(C4=CN=CN=C4)=C3)(C5=CC(C(F)F)=NC=C5)N=C2N)=CC=C1
其他名称	AZD 3839, AZD-3839
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	79 mg/mL (183.11 mM)
	Water	Insoluble
	Ethanol	Warmed: 79 mg/mL (183.11 mM)
In vivo	5% dimethylacetamide and 20% hydroxypropyl-??-cyclodextrin in 0.3 M gluconic acid, pH 3, or 0.3 M gluconic acid, pH 3.	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.18 mL	115.9 mL	231.8 mL
0.5 mM	4.64 mL	23.18 mL	46.36 mL
1 mM	2.32 mL	11.59 mL	23.18 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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