AZD5153 6-Hydroxy-2-naphthoic acid

Name: AZD5153 6-Hydroxy-2-naphthoic acid
SKU: A21852
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A21852

BET/BRD4 bromodomain 抑制剂

AZD5153 6-羟基-2-萘甲酸是 AZD5153 的 6-羟基-2-萘甲酸。AZD5153 是一种强效、选择性且可口服的 BET/BRD4 溴结构域抑制剂；其破坏 BRD4 的 IC50 为 1.7 nM。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥840.00	现货
10mg	¥1,505.00	现货
25mg	¥2,730.00	现货
50mg	¥4,410.00	现货
100mg	¥6,825.00	现货
*10mM 1mL in DMSO**	¥1,260.00	现货
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Data Sheet

SDS

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生物活性

Discription	AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.

产品信息

目录号	A21852
分子式	C36H41N7O6
分子量	667.75
CAS号	1869912-40-2
SMILES	O=C(C1=CC=C2C=C(O)C=CC2=C1)O.O=C3N(C)CCN(CCOC4=CC=C(C5CCN(C6=NN7C(C=C6)=NN=C7OC)CC5)C=C4)[C@@H]3C
其他名称	AZD-5153 HNT salt, AZD5153, AZD 5153
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	93 mg/mL (139.27 mM)
	Water	Insoluble
	Ethanol	Warmed: 25 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.98 mL	74.88 mL	149.76 mL
0.5 mM	3 mL	14.98 mL	29.95 mL
1 mM	1.5 mL	7.49 mL	14.98 mL
5 mM	0.3 mL	1.5 mL	3 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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