AZD5363
AZD5363 是一种强效的 AKT 抑制剂，在体内具有药效活性，有潜力作为单药治疗或联合治疗药物，用于治疗多种实体瘤和血液肿瘤。
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Adooq用户使用AZD5363发表的6篇文献
生物活性
| Discription | AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11759 |
|---|---|
| 分子式 | C21H25ClN6O2 |
| 分子量 | 428.9 |
| CAS号 | 1143532-39-1 |
| SMILES | C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
| 其他名称 | AZD 5363, AZD-5363 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 79 mg/mL (184.18 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.32 mL | 116.58 mL | 233.15 mL |
| 0.5 mM | 4.66 mL | 23.32 mL | 46.63 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1143532-39-1 | 1143532-39-1 供应商 | 1143532-39-1 花费 | 1143532-39-1 生产商 | 订购 1143532-39-1 | 1143532-39-1 代理商