产品详情
AZD5363是有效的AKT抑制剂,在体内具有药效学活性,有潜力作为单一疗法或联合用药来治疗一系列实体瘤和血液肿瘤。
In vitro | DMSO | 79 mg/mL (184.18 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.32 mL | 116.58 mL | 233.15 mL |
0.5 mM | 4.66 mL | 23.32 mL | 46.63 mL |
1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 428.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11759 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 428.9 |
Formula | C21H25ClN6O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1143532-39-1 |
Synonyms | AZD 5363, AZD-5363 |
SMILES | C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Afuresertib HCl
Afuresertib HCl,也称为GSK2110183,是具有潜在抗肿瘤活性的丝氨酸/苏氨酸蛋白激酶Akt(蛋白激酶B)的生物利…
ARQ-092 (Miransertib)
ARQ 092是一种口服活化,有效和选择性的AKT抑制剂,IC50值:5.0 nM(AKT1);4.5 nM(AKT2);16 nM(AKT3)。
10-DEBC HCl
10-DEBC HCl是Akt/PKB的选择性抑制剂。它抑制IGF-1刺激的磷酸化和Akt的激活(在2.5μM时完全抑制),抑制mTOR,p7…
Keywords:购买 AZD5363 | AZD5363 供应商 | 订购 AZD5363 | AZD5363 价格 | AZD5363 生产商 | 订单 AZD5363 | AZD5363 代理商 | 购买 1143532-39-1 | 1143532-39-1 供应商 | 订购 1143532-39-1 | 1143532-39-1 价格 | 1143532-39-1 生产商 | 订单 1143532-39-1 | 1143532-39-1 代理商|buy AZD5363 | AZD5363 Supplier | purchase AZD5363 | AZD5363 cost | AZD5363 manufacturer | order AZD5363 | AZD5363 distributor | buy 1143532-39-1 | 1143532-39-1 Supplier | purchase 1143532-39-1 | 1143532-39-1 cost | 1143532-39-1 manufacturer | order 1143532-39-1 | 1143532-39-1 distributor