AZD6482

目录号: A10112

PI3K inhibitor

AZD6482

AZD6482 Chemical Structure

CAS NO. 1173900-33-8

AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
25 mg
¥ 3,500.00
50 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 1,330.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.
Targets
PI3Kβ (Cell-free assay) PI3Kδ (Cell-free assay) DNA-PK (Cell-free assay) PI3Kα (Cell-free assay) PI3Kγ (Cell-free assay)
10 nM80 nM420 nM870 nM1090 nM
In vitro (25°C) DMSO 82 mg/mL (200.75 mM)
Water <1 mg/mL (<1 mM)
Ethanol 10 mg/mL (24.48 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.48 mL 122.4 mL 244.8 mL
0.5 mM 4.9 mL 24.48 mL 48.96 mL
1 mM 2.45 mL 12.24 mL 24.48 mL
5 mM 0.49 mL 2.45 mL 4.9 mL

*The above data is based on the productmolecular weight 408.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10112
MECHANISM OF ACTION Inhibitor
M. Wt 408.5
Formula C22H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1173900-33-8
Synonyms AZD-6482
SMILES CC1=CN2C(=O)C=C(N=C2C(=C1)[C@@H](C)NC3=CC=CC=C3C(=O)O)N4CCOCC4

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