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AZD6738

促销

ATR 抑制剂

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产品目录号: A15794

库存状态:中国现货中国现货

产品名 目录号 价格 数量
AZD6738 5mg A15794-5
¥ 1,000.00
AZD6738 10mg A15794-10
¥ 1,500.00
AZD6738 25mg A15794-25
¥ 3,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.

AZD6738

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Chemical Information

目录号 A15794
Mechanism of action Inhibitor
分子量 412.51
化学分子式 C20H24N6O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1352226-88-0
Synonyms AZD-6738, AZD 6738
SMILES code C[C@H]1N(C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(C5([S@](=O)(C)=N)CC5)=C2)CCOC1
化学名称 (R)-imino(methyl)(1-(6-((R)-3-methylmorpholino)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)cyclopropyl)-l6-sulfanone

生物活性

Description
AZD6738 is a potent inhibitor of ATR kinase activity with an IC50 of 1 nM against the isolated enzyme and 74 nM against ATR kinase-dependent CHK1 phosphorylation in cells.
Targets
ATR
1 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.24 mL 121.21 mL 242.42mL
0.5 mM 4.85 mL 24.24 mL 48.48 mL
1 mM 2.42 mL 12.12 mL 24.24 mL
5 mM 0.48 mL 2.42 mL 4.85 mL

*The above data is based on the productmolecular weight 412.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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