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Chk1 & Chk2 抑制剂

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产品目录号: A10113


产品名 目录号 价格 数量
AZD7762 5mg A10113-5
¥ 400.00
AZD7762 10mg A10113-10
¥ 700.00
AZD7762 25mg A10113-25
¥ 1,500.00
AZD7762 100mg A10113-100
¥ 5,800.00
AZD7762 10mM * 1mL in DMSO A10113-10mM-D
¥ 880.00



AZD7762 is a potent ATP-competitive checkpoint kinase inhibitor that drives checkpoint abrogation and potentiates DNA-targeted therapies.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10113
Mechanism of action Inhibitor
分子量 362.4
化学分子式 C17H19FN4O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 860352-01-8
Synonyms AZD-7762
SMILES code C1C[C@@H](CNC1)NC(=O)C2=C(C=C(S2)C3=CC(=CC=C3)F)NC(=O)N
化学名称 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide


AZD7762 is a potent ATP-competitive checkpoint kinase inhibitor that drives checkpoint abrogation and potentiates DNA-targeted therapies.
Chk1 (Cell-free assay) Chk2 (Cell-free assay)
5 nM<10 nM


Solubility (25°C)* In vitro DMSO 50 mg/mL (137.96 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.59 mL 137.97 mL 275.94mL
0.5 mM 5.52 mL 27.59 mL 55.19 mL
1 mM 2.76 mL 13.8 mL 27.59 mL
5 mM 0.55 mL 2.76 mL 5.52 mL

*The above data is based on the productmolecular weight 362.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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