AZD8330

目录号: A10115

MEK Inhibitor

AZD8330

AZD8330 Chemical Structure

CAS NO. 869357-68-6

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
50 mg
¥ 6,200.00
100 mg
¥ 10,800.00
10mM * 1mL in DMSO
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
Targets
ERK phosphorylation MEK1/2
0.4 nM7 nM
In vitro (25°C) DMSO 92 mg/mL (199.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol 92 mg/mL (199.46 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.68 mL 108.41 mL 216.83 mL
0.5 mM 4.34 mL 21.68 mL 43.37 mL
1 mM 2.17 mL 10.84 mL 21.68 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 461.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10115
MECHANISM OF ACTION Inhibitor
M. Wt 461.2
Formula C16H17FIN3O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869357-68-6
Synonyms AZD-8330
SMILES CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO

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