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PI3K??/PI3K?? 抑制剂

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产品目录号: A16352


产品名 目录号 价格 数量
AZD8835 5mg A16352-5
¥ 900.00
AZD8835 10mg A16352-10
¥ 1,600.00
AZD8835 50mg A16352-50
¥ 4,800.00



AZD8835 is a potent and selective inhibitor of PI3Kα and PI3Kδ with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).





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Chemical Information

目录号 A16352
Mechanism of action Inhibitor
分子量 469.54
化学分子式 C22H31N9O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1620576-64-8
Synonyms AZD 8835, AZD-8835
SMILES code O=C(N1CCC(C2=NN(CC)C(C3=NC(C4=NN=C(C(C)(C)C)O4)=C(N)N=C3)=N2)CC1)CCO
化学名称 1-(4-(5-(5-amino-6-(5-(tert-butyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1H-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one


AZD8835 is a potent and selective inhibitor of PI3Kα and PI3Kδ with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.49 mL 212.97mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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