|ErbB2 (Cell-free assay)||EGFR (Cell-free assay)||ErbB3 (Cell-free assay)|
|3 nM||4 nM||4 nM|
|In vitro (25°C)||DMSO||40 mg/mL (84.4 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||5 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||21.1 mL||105.51 mL||211.01 mL|
|0.5 mM||4.22 mL||21.1 mL||42.2 mL|
|1 mM||2.11 mL||10.55 mL||21.1 mL|
|5 mM||0.42 mL||2.11 mL||4.22 mL|
*The above data is based on the productmolecular weight 473.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
|Synonyms||AZD-8931, Momelotinib, Sapitinib|
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