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Azeliragon

Azeliragon

Name: Azeliragon
SKU: A20622

目录号: A20622

RAGE inhibitor

Azeliragon Chemical Structure

CAS NO. 603148-36-3

Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer??s disease (AD). Azeliragon also can cross the blood-brain barrier (BBB).

库存：现货

规格	价格	数量
5 mg	￥ 1,300.00
10 mg	￥ 2,230.00
50 mg	￥ 6,620.00
100 mg	￥ 13,250.00

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产品详情

生物活性

溶解度 *

In vitro	DMSO	90 mg/mL (169.13 mM)
	Water	Insoluble
	Ethanol	90 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.79 mL	93.96 mL	187.93 mL
0.5 mM	3.76 mL	18.79 mL	37.59 mL
1 mM	1.88 mL	9.4 mL	18.79 mL
5 mM	0.38 mL	1.88 mL	3.76 mL

*The above data is based on the productmolecular weight 532.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20622
M. Wt	532.12
Formula	C32H38ClN3O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	603148-36-3
Synonyms	TTP488, TTP 488, TTP-488; PF-04494700, PF 04494700, PF04494700
SMILES	ClC1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(CCCC)=NC(C(C=C4)=CC=C4OCCCN(CC)CC)=C3