Azilsartan (TAK-536)
目录号: A11775
AT1 Receptor Blocker
Azilsartan (TAK-536) 是一种血管紧张素II受体拮抗剂,用于治疗高血压。
| Discription | Azilsartan (TAK-536) is an angiotensin II receptor antagonist used in the treatment of hypertension. | ||
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| Targets |
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| 目录号 | A11775 |
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| 分子式 | C25H20N4O5 |
| 分子量 | 456.5 |
| CAS号 | 147403-03-0 |
| SMILES | CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)O |
| 其他名称 | TAK536 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 78 mg/mL (170.88 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.91 mL | 109.53 mL | 219.06 mL |
| 0.5 mM | 4.38 mL | 21.91 mL | 43.81 mL |
| 1 mM | 2.19 mL | 10.95 mL | 21.91 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2