B-Raf inhibitor 1 dihydrochloride
目录号: A21834
Raf kinase 抑制剂
B-Raf 抑制剂 1 二盐酸盐是一种强效的 Raf 激酶抑制剂,其 Kis 分别为 B-RafWT 1 nM、B-RafV600E 1 nM 和 C-Raf 0.3 nM。
Discription | B-Raf inhibitor 1 dihydrochloride is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. | ||
---|---|---|---|
Targets |
|
目录号 | A21834 |
---|---|
分子式 | C26H21Cl3N8 |
分子量 | 551.86 |
CAS号 | 1191385-19-9 |
SMILES | CC1=CC=C2C(C=CN=C2NC3=CC=C(Cl)C=C3)=C1NC4=NC=CC=C4C5=NC=NC6=C5N=CN6.[H]Cl.[H]Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 96 mg/mL (173.95 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.12 mL | 90.6 mL | 181.21 mL |
0.5 mM | 3.62 mL | 18.12 mL | 36.24 mL |
1 mM | 1.81 mL | 9.06 mL | 18.12 mL |
5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2