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B-Raf-inhibitor 1

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B-Raf 抑制剂

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产品目录号： A14122

库存状态：中国现货中国现货

产品名 目录号 价格 数量
B-Raf-inhibitor 1 10mg A14122-10
￥ 1,200.00
B-Raf-inhibitor 1 25mg A14122-25
￥ 2,500.00
B-Raf-inhibitor 1 50mg A14122-50
￥ 4,000.00

产品仅用于研究，不针对患者销售，望谅解.

产品简介

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively

B-Raf-inhibitor 1

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Chemical Information

目录号 A14122
Mechanism of action Inhibitor
分子量 478.94
化学分子式 C26H19ClN8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1093100-40-3
Synonyms B-Raf inhibitor1, B-Raf inhibitor-1
SMILES code CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6
化学名称 N1-(4-chlorophenyl)-6-Methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-

生物活性

Description
 B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.88 mL 104.4 mL 208.79mL
0.5 mM 4.18 mL 20.88 mL 41.76 mL
1 mM 2.09 mL 10.44 mL 20.88 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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