产品详情
B-Raf inhibitor 1是有效的选择性B-Raf抑制剂,对A375增殖和A375 p-ERK的细胞IC50分别为0.31 uM和2 nM。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.88 mL | 104.4 mL | 208.79 mL |
0.5 mM | 4.18 mL | 20.88 mL | 41.76 mL |
1 mM | 2.09 mL | 10.44 mL | 20.88 mL |
5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
*The above data is based on the productmolecular weight 478.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A14122 |
---|---|
MECHANISM OF ACTION | Inhibitor |
M. Wt | 478.94 |
Formula | C26H19ClN8 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1093100-40-3 |
Synonyms | B-Raf inhibitor1, B-Raf inhibitor-1 |
SMILES | CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6 |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Diazepinomicin
Diazepinomicin,也称为TLN-4601,是具有潜在抗肿瘤活性的RAS/RAF/MAPK信号传导途径的小分子抑制剂。
BRAF inhibitor
BRAF inhibitor是一种有效的braf抑制剂。
MLN2480 (BIIB-024)
MLN2480是临床试验中的一种口服选择性泛Raf激酶抑制剂。
HG6-64-1
HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor; more information can be found in Patent WO 2011090738.
RAF265 (CHIR-265)
RAF265(CHIR-265)是一种口服,高度选择性的RAF和VEGFR激酶抑制剂,可控制或正常化VEGFR-2,同时抑制B-raf和c-Ra…
Dabrafenib (GSK2118436A)
Dabrafenib是一种有效且选择性的B-RAF蛋白激酶抑制剂,具有V600E突变,目前正在临床试验中。
Keywords:购买 B-Raf-inhibitor 1 | B-Raf-inhibitor 1 供应商 | 订购 B-Raf-inhibitor 1 | B-Raf-inhibitor 1 价格 | B-Raf-inhibitor 1 生产商 | 订单 B-Raf-inhibitor 1 | B-Raf-inhibitor 1 代理商 | 购买 1093100-40-3| 1093100-40-3 供应商 | 订购 1093100-40-3 | 1093100-40-3 价格 | 1093100-40-3 生产商 | 订单 1093100-40-3 | 1093100-40-3 代理商|buy B-Raf-inhibitor 1 | B-Raf-inhibitor 1 Supplier | purchase B-Raf-inhibitor 1 | B-Raf-inhibitor 1 cost | B-Raf-inhibitor 1 manufacturer | order B-Raf-inhibitor 1 | B-Raf-inhibitor 1 distributor | buy 1093100-40-3| 1093100-40-3 Supplier | purchase 1093100-40-3 | 1093100-40-3 cost | 1093100-40-3 manufacturer | order 1093100-40-3 | 1093100-40-3 distributor