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BACE-1 inhibitor 1 (Compound 8a) is a potent BACE-1 inhibitor with an IC50 of 56 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.56 mL | 112.81 mL | 225.62 mL |
| 0.5 mM | 4.51 mL | 22.56 mL | 45.12 mL |
| 1 mM | 2.26 mL | 11.28 mL | 22.56 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.51 mL |
*The above data is based on the productmolecular weight 443.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19560 |
|---|---|
| M. Wt | 443.22 |
| Formula | C17H14BrF3N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1262858-14-9 |
| SMILES | BrC1=CC=C(C(NC2=CC=C(F)C([C@@]3(C(F)F)N=C(N)COC3)=C2)=O)N=C1 |
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