BACE1-IN-1

Name: BACE1-IN-1
SKU: A12183

目录号: A12183

BACE1 inhibitor

BACE1-IN-1 Chemical Structure

CAS NO. 1310347-50-2

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 6,750.00
5 mg	￥ 20,250.00
10 mg	￥ 34,500.00

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生物活性

BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.69 mL	128.43 mL	256.85 mL
0.5 mM	5.14 mL	25.69 mL	51.37 mL
1 mM	2.57 mL	12.84 mL	25.69 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 389.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12183
作用机制	Inhibitor (抑制剂)
M. Wt	389.33
Formula	C18H14F3N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1310347-50-2
SMILES	O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2