Baclofen
目录号: A18248
GABA 激动剂
巴氯芬是一种特异性针对 GABA-B 受体的 GABA 激动剂。巴氯芬是一种合成的氯苯基丁酸衍生物，用于治疗由于脊髓损伤和多发性硬化症引起的痉挛，具有肌肉松弛作用。它在脊髓和脊髓上层部位发挥作用，减少兴奋性传递。
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生物活性
| Discription | Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission. | |||||
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| Cell Research |
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产品信息
| 目录号 | A18248 |
|---|---|
| 分子式 | C10H12ClNO2 |
| 分子量 | 213.66 |
| CAS号 | 1134-47-0 |
| SMILES | O=C(O)CC(C1=CC=C(Cl)C=C1)CN |
| 其他名称 | Baclofen; Lioresal, Liofen, Gablofen; Baclon; Kemstro |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Insoluble | |
| Water | <1 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 46.8 mL | 234.02 mL | 468.03 mL |
| 0.5 mM | 9.36 mL | 46.8 mL | 93.61 mL |
| 1 mM | 4.68 mL | 23.4 mL | 46.8 mL |
| 5 mM | 0.94 mL | 4.68 mL | 9.36 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1134-47-0 | 1134-47-0 供应商 | 1134-47-0 花费 | 1134-47-0 生产商 | 订购 1134-47-0 | 1134-47-0 代理商