BAF312 (Siponimod)
目录号: A12906
S1PR1/S1PR5 抑制剂
BAF312 是一种新一代强效的鞘氨醇1-磷酸(S1P)受体激动剂,选择性作用于 S1P1 和 S1P5。
| Discription | BAF312 is a next-generation potent sphingosine 1-phosphate (S1P) receptor agonist, selective for S1P1 and S1P5. | ||
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| 目录号 | A12906 |
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| 分子式 | C29H35F3N2O3 |
| 分子量 | 516.6 |
| CAS号 | 1230487-00-9 |
| SMILES | CCC1=C(C=CC(=C1)C(=NOCC2=CC(=C(C=C2)C3CCCCC3)C(F)(F)F)C)CN4CC(C4)C(=O)O |
| 其他名称 | Siponimod |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 99 mg/mL (191.63 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 44 mg/mL (85.17 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.36 mL | 96.79 mL | 193.57 mL |
| 0.5 mM | 3.87 mL | 19.36 mL | 38.71 mL |
| 1 mM | 1.94 mL | 9.68 mL | 19.36 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.87 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2