Bafetinib (INNO-406)

目录号: A10119

Bcr-Abl inhibitor

Bafetinib (INNO-406)

Bafetinib (INNO-406) Chemical Structure

CAS NO. 859212-16-1

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,300.00
50 mg
¥ 3,900.00
100 mg
¥ 4,800.00
10mM * 1mL in DMSO
¥ 1,740.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Bafetinib ((INNO-406) is a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia.
Targets
Abl (Cell-free assay) Lyn (Cell-free assay)
5.8 nM19 nM
In vitro (25°C) DMSO 100 mg/mL (173.42 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.34 mL 86.72 mL 173.43 mL
0.5 mM 3.47 mL 17.34 mL 34.69 mL
1 mM 1.73 mL 8.67 mL 17.34 mL
5 mM 0.35 mL 1.73 mL 3.47 mL

*The above data is based on the productmolecular weight 576.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10119
MECHANISM OF ACTION Inhibitor
M. Wt 576.6
Formula C30H31F3N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 859212-16-1
Synonyms NS-187
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CC[C@@H](C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5

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