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Bafilomycin A1

目录号: A11961
ATPase 抑制剂
Bafilomycin A1 通过抑制大鼠肝癌细胞系 H-4-II-E 细胞中自噬体溶酶体的融合,阻止自噬泡的成熟。
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规格 价格 库存 数量
100µg
¥525.00
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500µg
¥1,330.00
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1mg
¥1,960.00
现货
5mg
¥4,830.00
现货
10mg
¥6,930.00
现货
25mg
¥10,255.00
现货
50mg
¥13,895.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Bafilomycin A1发表的1篇文献
  • Ravindra Pramod Deshpande, .et al. , EMBO Mol Med, 2025, Apr;17(4):797-822 PMID: 40087501
  • 生物活性
    Discription Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A11961
    分子式 C35H58O9
    分子量 622.84
    CAS号 88899-55-2
    SMILES C[C@H]1C/C(=C/C=C\[C@@H](C(OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 6 mg/mL (9.63 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 16.06 mL 80.28 mL 160.55 mL
    0.5 mM 3.21 mL 16.06 mL 32.11 mL
    1 mM 1.61 mL 8.03 mL 16.06 mL
    5 mM 0.32 mL 1.61 mL 3.21 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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