Bafilomycin A1

目录号: A11961

ATPase 抑制剂

Bafilomycin A1 Chemical Structure

CAS NO. 88899-55-2

Bafilomycin A1通过抑制大鼠肝癌细胞系H-4-II-E细胞中自噬体和溶酶体之间的融合来防止自噬泡的成熟。

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产品详情

生物活性

Bafilomycin A1通过抑制大鼠肝癌细胞系H-4-II-E细胞中自噬体和溶酶体之间的融合来防止自噬泡的成熟。

靶点信息

H+-ATPase
0.44 nM

溶解度 *

In vitro	DMSO	6 mg/mL (9.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.06 mL	80.28 mL	160.55 mL
0.5 mM	3.21 mL	16.06 mL	32.11 mL
1 mM	1.61 mL	8.03 mL	16.06 mL
5 mM	0.32 mL	1.61 mL	3.21 mL

*The above data is based on the productmolecular weight 622.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11961
作用机制	Inhibitor (抑制剂)
M. Wt	622.84
Formula	C35H58O9
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	88899-55-2
SMILES	C[C@H]1C/C(=C/C=C\[C@@H](C(OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C