Baricitinib phosphate

Name: Baricitinib phosphate
SKU: A15014
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15014

JAK 抑制剂

Baricitinib phosphate 是一种选择性的 JAK1 和 JAK2 抑制剂，其 IC50 分别为 5.9 nM 和 5.7 nM，相对于 JAK3 和 Tyk2 的选择性约为70倍和10倍，对 c-Met 和 Chk2 无抑制作用。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥350.00	现货
25mg	¥595.00	现货
50mg	¥770.00	现货
100mg	¥980.00	现货
500mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

Targets

Target	Value

产品信息

目录号	A15014
分子式	C16H20N7O6PS
分子量	469.41
CAS号	1187595-84-1
SMILES	CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O
其他名称	INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	85 mg/mL (181.08 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.3 mL	106.52 mL	213.03 mL
0.5 mM	4.26 mL	21.3 mL	42.61 mL
1 mM	2.13 mL	10.65 mL	21.3 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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