Baricitinib phosphate

目录号: A15014

JAK inhibitor

Baricitinib phosphate

Baricitinib phosphate Chemical Structure

CAS NO. 1187595-84-1

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

库存: 现货

规格 价格 数量
10 mg
¥ 700.00
25 mg
¥ 2,000.00
50 mg
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

生物活性

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.52 mL 213.03 mL
0.5 mM 4.26 mL 21.3 mL 42.61 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

产品技术资料

目录号 A15014
MECHANISM OF ACTION Inhibitor
M. Wt 469.41
Formula C16H20N7O6PS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1187595-84-1
Synonyms INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050
SMILES CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O

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