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Baricitinib phosphate

Baricitinib phosphate

Name: Baricitinib phosphate
SKU: A15014

目录号: A15014

JAK 抑制剂

Baricitinib phosphate Chemical Structure

CAS NO. 1187595-84-1

Baricitinib phosphate是一种选择性的JAK1和JAK2抑制剂，IC50为5.9 nM和5.7 nM，选择性是JAK3和Tyk2的?70和?10倍，对c-Met和Chk2没有抑制作用。

库存：现货

规格	价格	数量
10 mg	￥ 700.00
25 mg	￥ 2,000.00
50 mg	￥ 1,200.00

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生物活性

Baricitinib phosphate是一种选择性的JAK1和JAK2抑制剂，IC50为5.9 nM和5.7 nM，选择性是JAK3和Tyk2的?70和?10倍，对c-Met和Chk2没有抑制作用。

溶解度 *

In vitro	DMSO	85 mg/mL (181.08 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.3 mL	106.52 mL	213.03 mL
0.5 mM	4.26 mL	21.3 mL	42.61 mL
1 mM	2.13 mL	10.65 mL	21.3 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

*The above data is based on the productmolecular weight 469.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15014
作用机制	Inhibitor (抑制剂)
M. Wt	469.41
Formula	C16H20N7O6PS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1187595-84-1
Synonyms	INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050
SMILES	CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3.OP(=O)(O)O