Baricitinib (LY3009104)

Name: Baricitinib (LY3009104)
SKU: A11329
Price: 245 CNY
Rating: 5 (4 reviews)

目录号: A11329

JAK 抑制剂

4 篇发表文献

Baricitinib，也被称为INCB028050或LY3009104，是一种选择性的口服生物利用度的JAK1/JAK2抑制剂，对JAK1（5.9 nM）和JAK2（5.7 nM）具有纳摩尔级的效力。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥420.00	现货
25mg	¥595.00	现货
50mg	¥770.00	现货
100mg	¥980.00	现货
200mg	¥1,330.00	现货
500mg	¥2,240.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Baricitinib (LY3009104)发表的4篇文献

Hongli Liu, .et al. , Adv Rheumatol, 2023, Aug 28;63(1):45 PMID: 37641106

Dandan Wang, .et al. , Adv Rheumatol, 2023, May 16;63(1):22 PMID: 37194022

Yuki Sasaki, .et al. , JCI Insight, 2022, Apr 8;7(7) PMID: 35393946

Yutian Lei, .et al. , Kidney Int, 2021, Feb 16 PMID: 33607177

生物活性

Discription

Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11329
分子式	C16H17N7O2S
分子量	371.4
CAS号	1187594-09-7
SMILES	CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
其他名称	INCB28050, LY3009104
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	65 mg/mL (175 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.93 mL	134.63 mL	269.25 mL
0.5 mM	5.39 mL	26.93 mL	53.85 mL
1 mM	2.69 mL	13.46 mL	26.93 mL
5 mM	0.54 mL	2.69 mL	5.39 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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