Bavituximab is a recombinant monoclonal antibody that targets phosphatidylserine (PS), a key component of the tumor microenvironment. This antibody functions by suppressing tumor growth through dual mechanisms: direct targeting of tumor vasculature and reactivation of antitumor immune responses. In combination with chemotherapeutic agents Paclitaxel and Carboplatin, Bavituximab has demonstrated enhanced inhibitory effects on non-small-cell lung cancer, suggesting its potential utility in oncology research and therapeutic applications.
Bavituximab is a recombinant monoclonal antibody that targets phosphatidylserine (PS), a key component of the tumor microenvironment. This antibody functions by suppressing tumor growth through dual mechanisms: direct targeting of tumor vasculature and reactivation of antitumor immune responses. In combination with chemotherapeutic agents Paclitaxel and Carboplatin, Bavituximab has demonstrated enhanced inhibitory effects on non-small-cell lung cancer, suggesting its potential utility in oncology research and therapeutic applications.
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