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Bax channel blocker

目录号: A15335
Bax channel blocker
Bax 通道阻断剂是一种强效的抑制剂,能够抑制 Bax 介导的线粒体细胞色素 C 释放(IC50 = 0.52 μM)。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
5mg
¥525.00
现货
10mg
¥735.00
现货
25mg
¥1,330.00
现货
50mg
¥2,170.00
现货
100mg
¥3,290.00
现货
10mM * 1mL in DMSO
¥560.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Bax channel blocker发表的1篇文献
  • Stella Victorelli, .et al. , Nature, 2023, Oct;622(7983):627-636 PMID: 37821702
  • 生物活性
    Discription Bax channel blocker is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50 = 0.52 μM).
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A15335
    分子式 C19H23Br2Cl2N3O
    分子量 540.12
    CAS号 335165-68-9
    SMILES C1CN(CCN1)CC(CN2C3=C(C=C(C=C3)Br)C4=C2C=CC(=C4)Br)O.Cl.Cl
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 17 mg/mL (36.38 mM)
    Water Insoluble
    Ethanol 3 mg/mL (6.42 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.51 mL 92.57 mL 185.14 mL
    0.5 mM 3.7 mL 18.51 mL 37.03 mL
    1 mM 1.85 mL 9.26 mL 18.51 mL
    5 mM 0.37 mL 1.85 mL 3.7 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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