BAY 11-7085

Name: BAY 11-7085
SKU: A12470

目录号: A12470

κB/IKK 抑制剂

Product Citations (1)

BAY 11-7085 Chemical Structure

CAS NO. 196309-76-9

BAY 11-7085是TNFα诱导的IκBα磷酸化的不可逆抑制剂，IC50为10μM。

库存：现货

规格	价格	数量
10 mg	￥ 700.00
25 mg	￥ 1,500.00
50 mg	￥ 2,400.00
10mM * 1mL in DMSO	￥ 550.00

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生物活性

BAY 11-7085是TNFα诱导的IκBα磷酸化的不可逆抑制剂，IC50为10μM。

靶点信息

IκBα?phosphorylation
10 μM

溶解度 *

In vitro	DMSO	49 mg/mL (196.52 mM)
	Water	Insoluble
	Ethanol	49 mg/mL (196.52 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	40.11 mL	200.54 mL	401.07 mL
0.5 mM	8.02 mL	40.11 mL	80.21 mL
1 mM	4.01 mL	20.05 mL	40.11 mL
5 mM	0.8 mL	4.01 mL	8.02 mL

*The above data is based on the productmolecular weight 249.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12470
作用机制	Inhibitor (抑制剂)
M. Wt	249.33
Formula	C13H15NO2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	196309-76-9
Synonyms	Bay 11-7083, BAY11-7085
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N