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BAY 11-7085

??B/IKK 抑制剂

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产品目录号: A12470


产品名 目录号 价格 数量
BAY 11-7085 10mg A12470-10
¥ 700.00
BAY 11-7085 25mg A12470-25
¥ 1,500.00
BAY 11-7085 50mg A12470-50
¥ 2,400.00
BAY 11-7085 10mM * 1mL in DMSO A12470-10mM-D
¥ 550.00



BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM

BAY 11-7085




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 BAY 11-7085 发表的文献 (1)
  • Byungki Jang, .et al. The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells, Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Chemical Information

目录号 A12470
Mechanism of action Inhibitor
分子量 249.33
化学分子式 C13H15NO2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 196309-76-9
Synonyms Bay 11-7083, BAY11-7085
SMILES code CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)/C=C/C#N
化学名称 (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile


BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with IC50 of 10 μM
10 μM


Solubility (25°C)* In vitro DMSO 50 mg/mL (200.53 mM)
Water <1 mg/mL (<1 mM)
Ethanol 50 mg/mL (200.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.11 mL 200.54 mL 401.07mL
0.5 mM 8.02 mL 40.11 mL 80.21 mL
1 mM 4.01 mL 20.05 mL 40.11 mL
5 mM 0.8 mL 4.01 mL 8.02 mL

*The above data is based on the productmolecular weight 249.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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