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BAY 293

产品详情

生物活性

BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 21 nM.

溶解度 *

In vitro	DMSO	88 mg/mL (196.17 mM)
	Water	Insoluble
	Ethanol	88 mg/mL (196.17 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.29 mL	111.46 mL	222.92 mL
0.5 mM	4.46 mL	22.29 mL	44.58 mL
1 mM	2.23 mL	11.15 mL	22.29 mL
5 mM	0.45 mL	2.23 mL	4.46 mL

*The above data is based on the productmolecular weight 448.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18319
作用机制	Inhibitor (抑制剂)
M. Wt	448.59
Formula	C25H28N4O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2244904-70-7
Synonyms	BAY293, BAY-293
SMILES	CNCC1=C(C=CC=C1)C1=CSC(=C1)[C@@H](C)NC1=NC(C)=NC2=C1C=C(OC)C(OC)=C2