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BAY-677 is an inactive control for BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.98 mL | 124.89 mL | 249.78 mL |
| 0.5 mM | 5 mL | 24.98 mL | 49.96 mL |
| 1 mM | 2.5 mL | 12.49 mL | 24.98 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5 mL |
*The above data is based on the productmolecular weight 400.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19838 |
|---|---|
| M. Wt | 400.35 |
| Formula | C20H15F3N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2117404-84-7 |
| Synonyms | BAY 677, BAY677 |
| SMILES | N#CC1=NC=C([C@@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1 |
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