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BAY-678是人嗜中性粒细胞弹性蛋白酶（HNE）的口服生物利用型，高效，选择性和细胞渗透性抑制剂，IC50为20 nM。BAY-678还被结构基因组学联盟（SGC）提名为化学探针。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.98 mL | 124.89 mL | 249.78 mL |
| 0.5 mM | 5 mL | 24.98 mL | 49.96 mL |
| 1 mM | 2.5 mL | 12.49 mL | 24.98 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5 mL |
*The above data is based on the productmolecular weight 400.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16866 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 400.35 |
| Formula | C20H15F3N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 675103-36-3 |
| Synonyms | BAY 678, BAY678 |
| SMILES | N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1 |
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