BAY-8002
目录号: A18611
MCT1 抑制剂
BAY-8002 是一种强效、选择性、口服活性的 单羧酸转运蛋白1(MCT1)抑制剂,其在表达 MCT1 的 DLD-1 细胞中的 IC50 为 85 nM,对 MCT4 显示出极佳的选择性。具有抗肿瘤活性。
Discription | BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity. |
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目录号 | A18611 |
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分子式 | C20H14ClNO5S |
分子量 | 415.85 |
CAS号 | 724440-27-1 |
SMILES | O=C(O)C1=CC=CC=C1NC(C2=CC(S(=O)(C3=CC=CC=C3)=O)=CC=C2Cl)=O |
其他名称 | BAY8002, BAY 8002 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 73 mg/mL (175.54 mM) | |
Water | Insoluble | ||
Ethanol | 25 mg/mL (60.12 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.05 mL | 120.24 mL | 240.47 mL |
0.5 mM | 4.81 mL | 24.05 mL | 48.09 mL |
1 mM | 2.4 mL | 12.02 mL | 24.05 mL |
5 mM | 0.48 mL | 2.4 mL | 4.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2