产品详情

BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity.

溶解度 *

In vitro	DMSO	73 mg/mL (175.54 mM)
	Water	Insoluble
	Ethanol	25 mg/mL (60.12 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.05 mL	120.24 mL	240.47 mL
0.5 mM	4.81 mL	24.05 mL	48.09 mL
1 mM	2.4 mL	12.02 mL	24.05 mL
5 mM	0.48 mL	2.4 mL	4.81 mL

*The above data is based on the productmolecular weight 415.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18611
作用机制	Inhibitor (抑制剂)
M. Wt	415.85
Formula	C20H14ClNO5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	724440-27-1
Synonyms	BAY8002, BAY 8002
SMILES	O=C(O)C1=CC=CC=C1NC(C2=CC(S(=O)(C3=CC=CC=C3)=O)=CC=C2Cl)=O